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Frederic BOSCHINI, R&D Powder Manager GREEnMat

ULiège - GREEnMat laboratory
" Development of a new and fast method for the production of magnetic nanobeads for virus RNA extraction for performing PCR test. We produced more the 500,000 doses for federal testing center and our product has been widly used in Belgium and out of our borders. We aslo develop a method for producing high quantities of lysis buffer, guanidine thiocyanate (hundred liters/week), to release RNA from the virus and allow extraction. "
Contact: Dr BOSCHINI Frédéric Laboratoire GREEnMat University of Liège This email address is being protected from spambots. You need JavaScript enabled to view it. 0032-4-366-35-32

Frédéric Bouhon, Professor - Andy Jousten, PhD candidate - Xavier Miny, PhD candidate - Emmanuel Slautsky, Professor

ULiège et ULB 
" Belgium, like a large part of the world, is affected by the pandemic of the infectious disease called Covid-19, which is due to the spread of a coronavirus. In this extraordinary context, strong measures have been taken by the different authorities that make up the Belgian federal structure. This "Courrier hebdomadaire" intends to provide some initial legal observations on the way the Belgian State, with its institutional specificities, has begun to react to this extraordinary situation. It covers the period from 12 March to 30 March, during which Belgium gradually saw the establishment of an unprecedented peacetime emergency regime. The contribution is based on four observations. Firstly, the Belgian State has taken strong measures that meet its legal obligation to react to a risk to life of the Belgian citizens. Secondly, providing a centralised response to the health crisis linked to the Covid-19 pandemic is, in Belgium, complicated because of the existing division...

Frédéric Debiève, Professor (MD, PhD) - Arthur Colson, PhD fellow (MD) - Christophe Depoix, Postdoctoral (PhD) - Pierre Sonveaux, FNRS Senior Research Associate (PhD) - Corinne Hubinont, Professor (MD, PhD)

Cliniques universitaires Saint-Luc - UCLouvain - FRIA - FNRS
FD and CH are members of the cliniques universitaires Saint-Luc (CUSL). CD is a postdoctoral researcher at UCLouvain. AC is a PhD Fellow of the Belgian Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture (FRIA). PS is a Senior Research Associate of the Fonds National de la Recherche Scientifique (F.R.S-FNRS). - FNRS

" The novel coronavirus infection (COVID-19) is a global public health emergency. In several months, the infection has spread dramatically to the entire world and resulted in a major epidemic. In this context, pregnant women require particular attention in term of emerging infections because of the physiological changes in their immune and cardiopulmonary systems. The first analysis of 38 pregnant women with COVID-19 is quite reassuring since it did not report any maternal deaths, increased complications or vertical transmission. However, specific prospective studies about...

Frédéric Silvestre, Professor

" The main scientific question of this project aims to understand this inter-individual variability in the response to 2019-nCoV in human population, first during ageing process, second among population of same age. The first hypothesis that will be tested in this project is that epigenetic differences among human population can, at least partly, explain differences in the individual responses to SARS-CoV-2, and that this virus differentially affects the epigenome of different individuals during the infection. The second hypothesis that will be tested is that changes in the epigenome during ageing could increase the susceptibility of patients to SARS-CoV-2. "
Funding: To be searched
Publication References: - Fellous A, Earley RL, Silvestre F. Identification and expression of mangrove rivulus (Kryptolebias marmoratus) histone deacetylase (HDAC) and lysine acetyltransferase (KAT) genes. Gene, 691 (2019), 56-69. - Fellous A, Earley RL, Silvestre F. The Kdm/Kmt gene families in...

Georges Hübner, Professor

" Research Paper and associated expertise regarding the setup of a private equity fund aimed at collecting and pooling households' savings in order to restore the solvency of companies hit by the Covid-19 crisis through the subscription of preferred shares "
Publication References: Hübner, G. (2020), "Efficient Resource Allocation in the Context of the Coronavirus Crisis: Towards a Private Equity Fund Financed by Collective Savings", Revue Bancaire et Financière, Online edition 2020/4, 13 p.
Contact: https://www.financialforum.be/fr/articles/efficient-resource-allocation-context-coronavirus-crisis-towards-private-equity-fund

Géraldine Dessilly, PhD - Benoît Kabamba, Professor

" The objective of this project is to perform SARS CoV-2 infection of cells from Vero E6 line. With a view to -Study the information of the infection on the immune activation pathways and the metabolic pathways within the cells - Perform virus viability assays in different environments and analyze the effectiveness of the hygiene measures taken to prevent transmission of the virus into the environment. - Study the neutralization and the cytopathogenic effect by antibodies from clinical samples "
Funding: own funding
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it., Professor UCLouvain/Cliniques universitaires St-Luc This email address is being protected from spambots. You need JavaScript enabled to view it., PhD UCLouvain

Gilles Bruylants, Professor - Ivan Jabin, Professor - Vincent Raussens, Professor

" This project aims at developing soluble anti-SARS-CoV-2 virus immunoglobins (IgM and IgG) detection systems based on calixarene coated silver nanoparticles functionalized with viral antigens. These particles could advantageously replace gold nanoparticles (10x more efficient in light extinction) in Lateral Flow ImmunoAssays and Immunoturbidimetry tests. "
Funding: ULB Special COVID-19 Call
Publication References: "Controlled Functionalisation of Gold Nanoparticles with Mixtures of Calix[4]arenes revealed by Infra-red Spectroscopy". Valkenier, H.; Malytskyi, V.; Blond, P.; Retout, M.; Mattiuzzi, A.; Goole, J.; Raussens, V.; Jabin, I.; Bruylants, G., Langmuir 2017, 33, 8253-8259. "Extremely robust and post-functionalizable gold nanoparticles coated with calix[4]arenes via metal–carbon bonds". Troian-Gautier, L.; Valkenier, H.; Mattiuzzi, A.; Jabin, I.; Van den Brande, N.; Van Mele, B.; Hubert, J.; Reniers, F.; Bruylants, G.; Lagrost, C.; Leroux, Y., Chem. Commun. 2016, 52...

Gilles Darcis, FNRS Post-doctorate Clinical Master Specialist

ULiège, CHU - FNRS
" We aim to compare various diagnostic tools (swabs, saliva, serology, antigen detection) in order to define the best one depending on the clinical presentation and the duration of the disease. "
Funding: Fonds Léon Fredericq FNRS
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Gilles Darcis, FNRS Post-doctorate Clinical Master Specialist

ULiège, CHU - FNRS
" We aim to define the clinical characteristics associated with the production and the level of neutralizing antibodies (NAbs) in COVID19 recovered patients. In particular, we will investigate whether the development of a strong and persistent humoral immune response takes place in severely affected, individuals with mild symptoms or asymptomatic individuals. We will also study the study the persistence of NAbs overtime. "
Funding: Fonds Léon Frédéricq FNRS
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Glenn Magerman, Professor - Mathias Dewatripont, Professor - Bram De Rock, Professor

" Learning from the curve is a voluntary and open source research project on COVID-19 and economics. It is a joint initiative of researchers in economics at ECARES, Solvay, ULB. Our mission is to provide detailed and real-time information and visualizations on COVID-19 and economics for the general public and the press, to serve as a platform for research collaboration on these topics, to understand the impact of COVID-19 on the economic tissue of countries and regions, to provide policy recommendations based on scientific arguments supported by data analytics. Learning from the curve started as a voluntary effort of faculty and students in empirical economics at ECARES. We are also very grateful for funding from the Special COVID-19 ULB grant. None of this would be possible without either. We call data from various sources, which are referenced in the respective dashboards and articles. We provide data sources and code on our Github organization. All publicly available data, code...

Greet Kerckhofs, Professor

" According to current guidelines from several health organization, the use of (homemade) textile face masks is recommended in order to slow the spread of the COVID-19. Currently, however, guidelines are very limited regarding the textiles to use (for the envelope), and the best suited filter material to be used in these types of masks. The general goal of this project is to provide reliable, consistent and science-based recommendations and guidelines about the preferred design for (homemade) textile face masks, as well as about the preferred materials to use for the textile envelope and the filter material. We will first determine the microstructure of different materials, giving us information on the filter efficiency (mechanical) and breathability of different materials and masks. Then, we will investigate the variability in filter efficiency and breathability of different material combinations. Finally, we will assess the aging of the filter material under humid...

Grégoire Lits, Professor - Louise-Amélie Cougnon, Doctor - Alexandre Heeren, FNRS Research Associate - Bernard Hanseeuw, Professor

UCLouvain - FNRS
" Our interdisciplinary project (communication science, psychology, medical science) aims at measuring the evolution of the Covid-19 infodemic in Belgium through quantitative surveys and qualitative interviews. One work package of the project focus on French-speaking Belgium only (three waves survey, interviews). Another work package covers all Belgium (two waves survey) as part of an international comparison project in 8 countries. "
Funding: None at the moment.

Publication References : ORM Research report (May 2020) : Analyse de « l’infodémie » de Covid-19 en Belgique francophone URL : https://osf.io/preprints/socarxiv/wsuj3/
Contact : Grégoire Lits, This email address is being protected from spambots. You need JavaScript enabled to view it. https://uclouvain.be/fr/instituts-recherche/ilc/ilc-covid-19.html

Gregory Ponthiere, Professor

" This research project aims at studying the conditions under which the modern welfare state could build a kind of epidemics insurance, while paying a particular attention to the issue of fairness. The global objective of saving lives may be associated to policies that have undesirable distributive effects, against ideals of social justice. The project aims at finding ways to make mass prevention and equity compatible. "
Funding: This project will be part of my research load at UCLouvain, within the Hoover Chair in Economic ans Social Ethics.
Publication References: Fleurbaey, M., Ponthiere, G. (2013). Prevention against Equality ? Journal of Public Economics. Fleurbaey, M., Leroux, ML, Ponthiere, G. (2014). Compensating the dead. Journal of Mathematical Economics. Fleurbaey, M., Leroux, ML., Pestieau, P., Ponthiere G. (2016). Fair retirement under risk lifetime. International Economic Review. Leroux, ML., Ponthiere, G. (2018). Working time regulations, unequal lifetime and...

Guy Jerusalem, Professor

CHU Liege/ULiège
" La nouvelle pandémie COVID-19 modifie la prise en charge des patients oncologiques. Le premier objectif de notre projet est d'étudier la sécurité de la poursuite des traitements systémiques anti-tumoraux dans le contexte actuel de pandémie. Le deuxième objectif est de comprendre les inquiétudes et les ressentis de nos patients par rapport au risque d'attraper l'infection et leurs conséquences. Le troisième objectif est d'évaluer le taux d'infection et de séroconversion asymptomatique chez nos patients en comparaison à la population globale. Le quatrième objectif est de mieux comprendre les raisons de détresse du personnel soignant en oncologie afin de mieux organiser des mesures de soutien psychologique. "
Funding: Fondation Leon Frederic Fonds propres Oncologie Médicale
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

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Brussels & Wallonia against COVID19