ULB - FNRS - Royal Academy of Sciences, Letters and Fine Arts of Belgium
" The "Data against Corona task force" aim is to analyze data on the spread of the virus, making use of telecom- and epidemiological data. Based on this information the task force's goal is to: Take action in containing the rising number of infections, leveling the peak amount, and thus limiting the number of patients in hospital at the same time; Take measures to lower the infection curve; Provide a detailed assessment of the measures taken to contain the contagion. The role of the Ethics committee is to review the output of the "Data Against Corona" taskforce and to provide an ethical advice to the Steering Committee. The committee will highlight potential ethical conflicts arising from decisions taken based on the collection and analysis of the telecom and health data, such as : - Is the collection of information aligned with the concept of data protection ? - Are there potential & actual biases in the...

Read more: Jean-Noël Missa, Professor, FNRS Research Director

FNRS, UNamur, Royal Academy of Sciences, Letters and Fine Arts of Belgium
" Modelling the Covid-19 with a view to showing the importance of contact habits for the choice of an appropriate lockdown exit strategy. "
Funding: Own funding
Publication References: "Because Culture Matters, There is No One-Size-Fits-All Strategy of Exit from Cov-19 Lockdown", VoxEU article, London.
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it. This email address is being protected from spambots. You need JavaScript enabled to view it.
Comment: Main paper about to be submitted.

UMONS
" The 2019 coronavirus disease (COVID-19) pandemic is a public health emergency of international concern. Authorities and population are facing a global health crisis which pose a challenge to adapt quickly and effectively. The aim of this preliminary study was to survey the general public in Belgium to better understand their levels of psychological impact, anxiety and stress during the initial stage of containment. The data also explored tips and tricks immediately adopt by the population to manage containment. From 20 March to 28 March 2020, we conducted an online survey using snowball sampling techniques on social network. The online survey collected information on demographic data, stress level in the past 7 days, knowledge and concerns about COVID-19 and the impact of using technologies for taking information and stay connected to others, precautionary measures (tips and tricks) during the beginning of containment, and additional information required with respect to...

Read more: Jennifer Denis, PhD in psychology research and teaching associate

Chemical Engineering ULiège & CRM Group - FNRS
" The Chemical Engineering Department of the Faculty of Applied Sciences of the University of Liège has been producing protective visors by 3D printing since April 4 and provides various hospital services (CHU, Citadelle, Bois de l'Abbaye), rest homes, associations and health care practices. A team of members of the Department has been set up to ensure 24-hour production, which means that up to 90 visors can now be produced per day depending on demand. As the days go by, production optimization continues to lighten components, produce faster and reduce the amount of raw material needed. The Department also receives visor supports produced by 3D printing by people from the Metallurgical Research Centre (CRM), a privileged partner of the Faculty, in order to equip them with plastic sheets to produce visors. This equipment is then distributed with the rest of the production from Chemical Engineering. The milestone of 1000 visors...

Read more: Jérôme Schruyers, Researcher - Alexandre Léonard, Research logistician - Carlos Mendoza, Postdoc -...

UMONS, ULB, Sciensano
" A new type of biosensor to characterize in details antibodies specific for antigens of SARS-COV-2. "
Funding: UMONS
Publication References: E. Gosselin, O Denis, A. Van Cauwenberge, J. Conti, JJ Vanden Eynde, K. Huygen, J. De Coninck, "Quantification of the trichothecene Verrucarin-A in environmental samples using an antibody-based spectroscopic biosensor", Sensor Actuat. B.-Chem., 2012, 166-167, 549-555.
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

ULB, Faculty of Medicine, and Erasme Hospital
Suivi longitudinal de biomarqueurs sériques et urinaires de l'atteinte rénale aiguë associée au COVID-19 : impacts diagnostique et pronostique. " L'objectif principal de cette étude est de caractériser l'atteinte rénale aiguë par le virus SARS-COV2 chez des patients hospitalisés présentant une maladie COVID-19 à l'aide de biomarqueurs sériques et urinaires précoces et spécifiques à certains segments du néphron. L'objectif secondaire est d'établir une corrélation entre l'évolution de ces marqueurs observée durant la phase aiguë de l'insuffisance rénale et le passage éventuel à un stade chronique. "
Funding: Crédit Urgent de Recherche (CUR) sollicité auprès du FNRS
Publication References: BUNEL V, SOUARD F, ANTOINE M-H, STEVIGNY C, NORTIER JL. Nephrotoxicity of Natural Products: Aristolochic Acid and Fungal Toxins. In McQueen C.A., Comprehensive Toxicology, Third Edition. Vol 14, Oxford Elsevier Ltd (2018), pp 340-379. BUNEL V, TOURNAY Y...

Read more: Joëlle Nortier, Dr

Hôpital Erasme - ULB
" Background: In the Covid-19 pandemic context, all healthcare teams face clinical, organizational and technical challenges given the contagion, severity and mortality characteristics of the disease. Methods: A cross-sectional multicentric study (NCT04344145) aiming to compare levels of burnout, emotional distress and needs between frontline Covid-19 and non-Covid-19 healthcare workers has been conducted between April 16th and May 25th. Physicians, nurses and physiotherapists were recruited from emergency care units and Covid-19 care units (target group) and from non-Covid-19 care units (control group) from Erasme Hospital, Jolimont-Lobbes Hospital and Mons-Warquignies Hospital (N = 603). Participants completed self-reported questionnaires and scales. A mixed-mode data collection was carried out, either in paper form or web-based form. Assessment provided socio-demographic characteristics and professional information. It also measured professional fulfillment and...

Read more: Julien Tiete, Dr

UMONS
" The UMONS Health Research Institute, on the initiative of Justine Gaugue, Laurence Ris and Mandy Rossignol, in collaboration with the MUMONS, have set up a user-friendly and pleasant website (www.home-stress-home.com) for children and young people, containing information, resources and a link to an online survey to assess anxiety levels. The data will be collected for research purposes to better understand the development of anxiety disorders in often neglected populations: the children and the young adults in school or early working life. This interface, based on the results of the survey, will make it possible to provide personalized feedback to the user, in order to direct him/her towards relaxation strategies or specialists if the level of anxiety measured is very high. Other surveys and tools will be added later on to allow longitudinal monitoring of the impact on mental and physical health of the stress generated by the current crisis. The objective is to develop this...

Read more: Justine Gaugue, Professor, Laurence Ris, Professor - Mandy Rossignol, Professor

ULB
" Inhaled ivermectin against COVID-19 study. Development of solution for nebulisation - preclinical safety and efficacy in animal models and clinical evaluation. CORONAVIRUS 2020 (CUR) research project submitted to FNRS on May 1, 2020. "
Funding: FNRS (requested)
Contact: Professor Karim Amighi Laboratory of Pharmaceutics and biopharmaceutics Université libre de Bruxelles (ULB) Faculty of Pharmacy Campus Plaine, CP-207 Boulevard du Triomphe, B-1050 Brussels - Belgium This email address is being protected from spambots. You need JavaScript enabled to view it.

ULiège
" Since SARS-CoV-2 testing began at the CHU of Liège we have been carrying out regular whole genome sequencing (WGS) of COVID-19 samples. At the time of writing we have uploaded 187 viral genomes to https://nextstrain.org/ (almost half of the 393 from Belgium). We have carried out regular WGS to monitor the evolution of viral haplotypes. Where possible we have concentrated on health care workers with the goal of identifying clusters of transmission. This included a cluster of seven individuals who were tested on the Roche cobas® instrument using the SARS-CoV-2 test, all were positive for the ORF1ab assay, but negative for the second E-gene assay. To date we have WGS data from four of these individuals, all share identical viral genomes and a SNP in the E-gene has been identified as the most probable cause of the test failure. This observation highlights the importance of redundancy in SARS-CoV-2 assays, especially as some testing regimes recommend an E-gene assay as a primary...

Read more: Keith Durkin, Dr - Maria Artesi, Dr - Sébastien Bontems, Dr - Marie-Pierre Hayette, Dr- Vincent...

UCLouvain
" I have been asked by the IATDMCT to pilot a review sumarizing the potential interactions that it could have between investigational COVID antivirals and immunosuppressants (used to avoid rejection in solid organ transplantation) "
Publication References: PubMed ID=32304488 Pharmacologic treatment of transplant recipients infected with SARS-CoV-2: considerations regarding therapeutic drug monitoring and drug-drug interactions. Ther Drug Monit. 2020 Apr 15. doi: 10.1097/FTD.0000000000000761. [Epub ahead of print]
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

ULiège, GIGA-Research
" Development of specific antigens to allow the detection of circulating antibodies against SARS-CoV-2. Our aim is to contribute to the development of serological tests that could help identifying the people previously infected by SARS-CoV-2 and detect the presence of neutralizing antibodies, which would predict an individual protection against COVID-19. With the help of local renowned companies, we are currently testing various antigens and optimizing their production. "
Contact: Dr. Laurence Delacroix (This email address is being protected from spambots. You need JavaScript enabled to view it.), Neurodevelopmental Biology, GIGA-Neurosciences and GIGA-Stem Cells, 15 avenue Hippocrate, CHU-B36, B-4000 Liège). Dr. Marielle Lebrun (This email address is being protected from spambots. You need JavaScript enabled to view it.) and Pr. Catherine Sadzot (This email address is being protected from spambots. You need JavaScript enabled to view it.), laboratory of Immunology and Virology, GIGA-I3, 11 Avenue de l'hôpital, 4000 Liège.

ULiège
" The first objectives of our approach was to strongly increase the testing capacity for virus by using protocols that are as effective as possible and above all not very dependent on the external sources of consumables and reagents whose supply is threatened. The ULiege testing platform can analyse more than 3000 samples per day and is member on the National testing platform. "
Contact: Prof Fabrice BUREAU Vice-Recteur à la Recherche, Université de Liège Place du 20-Août, 7 B-4000, Liège Belgique Tél: +32 4 366 32 14 Prof Laurent GILLET Université de Liège Quartier Vallée, 2 Avenue de Cureghem, 10 B-4000, Liège Belgique Tél: +32 4 366 42 86

UCLouvain, Datatext
“The project aims at measuring the impact of the Covid-19 crisis on the French-speaking Belgium population through the analysis of discourses on social media. In particular, we work on an open corpus of (today) 4.000 tweets from politicians, 30.000 from the media and 100.000 from the population. All messages include a Covid-19 related expression. We focus on three main research topics: (1) the diachronic evolution of discourses, from the emergence of the disease in China to reopening plans, through lockdown measures; (2) the impact of political discourse on the acceptance of measures by citizens and (3) the role of the language used by the media in measures’ acceptance and anxiety of the population.”
Funding: Seeking funding 
Contact: Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.  Website: https://uclouvain.be/instituts-recherche/ilc/miil/reseaux-sociaux.html 

ULB and CHU-Charleroi
" MAker Study for COVID-19 Patient follow-up in intensive Care Unit (MASC-19) Around 5-10 % of patients suffering from COVID-19 symptom aggravation require intensive care. Among them half will die. COVID-19 is often compared to sepsis however few are known about this pathology and physicians are unable to discriminate which patients will suffer from severe symptoms. For this reason, Mask-19 project, which gathers CHU-Charleroi, the Faculties of Medicine and Pharmacy (ULB) and CNRS (France), will investigate markers in sera of COVID-19 patients collected in March and April 2020. They will be compared to septic patients by metabolomics and molecular networks for a better follow up of this specific patients "
Funding: COVID-ULB
Contact: Prof. Dr Pierre Van Antwerpen Dean of the Faculty of Pharmacy RD3- Pharmacognosy, Bioanalysis, Drug Discovery and Analytical Platform of the Faculty of Pharmacy This email address is being protected from spambots. You need JavaScript enabled to view it. +3226505263 +3226505249...

Read more: M. Piagnerelli, Professor, CHU-Charleroi-ULB - K. Zouaoui Boudjeltia, Professor, CHU-Charleroi-ULB...