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Technology & devices

Jean-Paul Deslypere, MD

Aesculape CRO Belgium BV
" Treatment of COVID 19 complications with antibodies "
Funding: partly public partly private
Contact : This email address is being protected from spambots. You need JavaScript enabled to view it. 0492 735931

Joël De Coninck, Professor

UMONS, ULB, Sciensano
" A new type of biosensor to characterize in details antibodies specific for antigens of SARS-COV-2. "
Funding: UMONS
Publication References: E. Gosselin, O Denis, A. Van Cauwenberge, J. Conti, JJ Vanden Eynde, K. Huygen, J. De Coninck, "Quantification of the trichothecene Verrucarin-A in environmental samples using an antibody-based spectroscopic biosensor", Sensor Actuat. B.-Chem., 2012, 166-167, 549-555.
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Khanh TRAN DUY

3D-Side S.A.
" "- 3D printing of swabs in SLS - 3D printing of valves - 3D printing of connectors for respiratory systems - Advice on guidelines on the manufacturing and post processing of such devices." "
Contact: Khanh TRAN DUY This email address is being protected from spambots. You need JavaScript enabled to view it.

Laurent Gillet, Professor - Fabrice Bureau, Professor

ULiège
" The first objectives of our approach was to strongly increase the testing capacity for virus by using protocols that are as effective as possible and above all not very dependent on the external sources of consumables and reagents whose supply is threatened. The ULiege testing platform can analyse more than 3000 samples per day and is member on the National testing platform. "
Contact: Prof Fabrice BUREAU Vice-Recteur à la Recherche, Université de Liège Place du 20-Août, 7 B-4000, Liège Belgique Tél: +32 4 366 32 14 Prof Laurent GILLET Université de Liège Quartier Vallée, 2 Avenue de Cureghem, 10 B-4000, Liège Belgique Tél: +32 4 366 42 86

Michael Jeanty, Managing Director

BECARV SA
" BECARV supplies and install solution and equipement for labs, such as modular biosafety cabinets, air purifier for containment of a room, filter units, etc "
Contact: www.becarv.be Michaël Jeanty This email address is being protected from spambots. You need JavaScript enabled to view it.

Olivier Debeir, Professor - Olivier Van Hove, Kinesiologist

ULB/ERASME
" Severe COVID-19 patients have a greater risk of long-term health issues and sometimes develop permanent lung damage or fibrosis needing a long treatment to enhance their quality of life. The project aims to better quantify the breathing parameters of a patient to assess his revalidation evolution. A 3D image acquisition based system, provides contacless and non invasive measure. The system can be used as a complementary diagnosis tools as well for a quantitative follow up. "
Funding: So far the project is supported by volunteering inside the ULB/Laboratory of Image Synthesis and Analysis (LISA) and the Erasme Hospital
Contact: Olivier Debeir < This email address is being protected from spambots. You need JavaScript enabled to view it.> & Olivier Van Hove < This email address is being protected from spambots. You need JavaScript enabled to view it.>

Olivier DURANTEAU, Doctor

Erasme Hospital
" Precise the frequency of thrombosis events in COVID19 patients "
Funding: No need
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Pierre-Hugues Stefanuto, PhD

ULiège 
" My main research interest is the development of complete analytical solutions for biomedical applications. I mostly focus on breath and other volatile matrices characterization. "
Publication References: Zanella, D., HENKET, M., SCHLEICH, F., Louis, R., Focant, J.-F., & Stefanuto, P.-H. (2019). Multi-matrices screening for untargeted volatilomics by GC×GC-TOFMS. European Respiratory Journal. Supplement, 54, 4272. Purcaro, G.* , Stefanuto, P.-H.* , Flavio, F., Marco, B., Wieland-Alter, W., Wright, P., & Hill, J. (2018, March). SPME-GC×GC-TOF MS fingerprint of virally-infected cell culture: Sample preparation optimization and data processing evaluation. Analytica Chimica Acta. SCHLEICH, F., Zanella, D., Stefanuto, P.-H., Dallinga, J., HENKET, M., Wouters, E. F. M., Van Steen, K., Van Schooten, F., Focant, J.-F., & Louis, R. (2019). Exhaled Volatile Organic Compounds Are Able to Discriminate Between Neutrophilic and Eosinophilic Asthma. AMERICAN JOURNAL OF...

Roger Cocle, CEO

Any-Shape
" Production of nasopharyngeal swabs using 3D printing "
Contact: Roger Cocle CEO This email address is being protected from spambots. You need JavaScript enabled to view it.

Saïd Mahmoudi, Professor - Thierry Dutoit, Full Professor - Sidi Ahmed Mahmoudi, Professor- Xavier Lessage, Eng - Sohaib Laraba, Eng - Omar Seddati, Phd - Mohammed Amin Belarbi, Eng - Olivier Debauche, Eng

UMONS - Faculty of Engineering - ILIA and ISIA Departments
" This study allows an early Covid-19 diagnosis by using AI and explainable based classification and detection methods applied to CT and X-ray datasets. Many datasets form several hospitals in Belgium are used. The goal of the project is to use AI based methods to identify Covid-19 patients. Explainable AI methods are used to provide efficient interpretation and visualization tools for the classification and detection results obtained. The second goal of this project is to create a benchmark dataset composed of chest CT and X-ray database related to Covid-19 disease. To this aim, a semi-automatic annotation tool is developed in order to allow fast image annotation by radiologists. - Explainable artificial intelligence applied to Covid-19 detection based on CT and X-ray images. - Annotation tool development to build a benchmark database. "
Funding: University of Mons - Faculty of Engineering
Publication References: ...

Serge Goldman, Scientific Director

CMMI
" The Center of Microscopy and Molecular Imaging (CMMI) is currently involved in establishing an accurate SARS-CoV-2 virus distribution topography in the organs and various cells of patients who died in COVID-19 units by providing immunohistochemistry and electron microscopy services (study director Pr. Isabelle Salmon). We have also developed and are currently offering preclinical multimodal quantitative imaging - of lung inflammation - of bacterial population (pathogen or no pathogen) - and of viral infection by isotopic imaging. All these models enable the understanding of pulmonary pathological features caused by SARS-viruses such as CoVID-19. From molecular to humanized animal models, the CMMI provides customized imaging solutions to research projects on Coronavirus The CMMI is also a proud partner of the ULB diagnostic platform set-up in Gosselies to face the epidemic of SARS-CoV2. "
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.
Comment: The CMMI was co-founded by ULB et UMons and is supported...

Serge Habraken, Professor

ULiège
" The Centre Spatial de Liege is developing a process for mask recycling by cleaning, decontamination and dehydradation. The process combines ethanol/water mix cleaning with an innovative outgassing step under vacuum. The decontamination is already proven thanks to the collaboration with the Veterinary Faculty . The outgassing step aims to retrieve mask performance (mainly filtration efficiency) close to original. "
Funding: No, internal ULiege project
Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Sofia Morra, FNRS Research Fellow

ULB, Hôpital Erasme - FNRS
Lung injury, endothelial dysfunction and the role of RAAS during SARS-CoV-2 invection. " The first case of a person infected with SARS-Cov-2 virus can be tracked back on November the 17th, 2019, in China. On March 11, 2020, the World Health Organization (WHO) declared COVID-19 outbreak a pandemic. On April 13, COVID-19 is affecting 210 countries and territories worldwide, about 2 million positive cases have been officially declared along with 115.000 deaths. The real number of infected and deaths is scarily higher, considering that up to 65% people are asymptomatic and thus, not tested. The percentage of patients with COVID-19 needed for intensive care unit (ICU) varied from 5 to 32% in Wuhan, China. It was up to 9% in Lombardy, Italy. According to available data from Lombardy, 99% of patients admitted to the ICU needed respiratory support (88% invasive ventilation, 11% non invasive ventilation). In this unprecedented time, while SARS-Cov-2 virus is halting...

Stéphane Lucas, Full Professor - Richard Coos, Engineer

UNamur
" The goal is to solve one of the shortage in the COVID19 diagnostic since the lack of this specific sampling equipment also seriously impedes the diagnostic capacity. 3D printing technologies and coatings deposited by low pressure plasma are applied to develop new generation of swabs and collection tubes. The general purpose for the swabs is to optimize the design in order to maximize the collection and minimize the pain. This involves design of swab tip cavity by fluid mecanic and 3D CAD/CAM, roughness adpatation, plasma surface treatement, surface energy evaluation, wettability evaluation of nasopharyngeal samples, sampling performance by housekeeping gene evaluation (GaPDH ), ..... The general comfort of usage of various designs is also evaluated on humans. The general purpose for the collection tube is to accomodate the new swabs, but also to minimize the number of operation post-sampling. Also, opening the tube and transfer of the content to eppendorf in one single...

Stéphanie Roosa, Program Leader Biotechnology - Thomas Godfroid, Scientific Leader Plasma Technology - Marie-Eve Druart, Scientific Leader Wet Coatings

Materia Nova
" Based on its expertise on surface treatments and biotechnology, Materia Nova is actively working on the development of decontamination process or anti-viral surface treatments. On the one one hand, plasma technology can be used to decontaminate surfaces or fabric, like sanitary masks. Beyond masks, this technique can be used for the sterilization of medical parts (respirator tubing, surgical instruments...) even sensitive to temperature. The technology can be declined in the form of a small system that could also be useful in structures other than hospitals such as nursing homes, shops... On the other hand, the knowledge of Materia Nova in wet and dry functional coatings dedicated to various properties and applications (transport, health, energy,…) helps to investigate the anti-viral surface treatment. Due to this large panel of technologies (plasma deposition, sol-gel, organic coating or electrodeposition), the coatings or the combination of coatings can be applied on...

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Tél : +32 2 504 92 11

info@COVID19-WB.be

Brussels & Wallonia against COVID19