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Biosensors

Joël De Coninck, Professor

UMONS, ULB, Sciensano
" A new type of biosensor to characterize in details antibodies specific for antigens of SARS-COV-2. "
Funding: UMONS
Publication References: E. Gosselin, O Denis, A. Van Cauwenberge, J. Conti, JJ Vanden Eynde, K. Huygen, J. De Coninck, "Quantification of the trichothecene Verrucarin-A in environmental samples using an antibody-based spectroscopic biosensor", Sensor Actuat. B.-Chem., 2012, 166-167, 549-555.
Contact: joel.deconinck@umons.ac.be

Olivier Debeir, Professor - Olivier Van Hove, Kinesiologist

ULB/ERASME
" Severe COVID-19 patients have a greater risk of long-term health issues and sometimes develop permanent lung damage or fibrosis needing a long treatment to enhance their quality of life. The project aims to better quantify the breathing parameters of a patient to assess his revalidation evolution. A 3D image acquisition based system, provides contacless and non invasive measure. The system can be used as a complementary diagnosis tools as well for a quantitative follow up. "
Funding: So far the project is supported by volunteering inside the ULB/Laboratory of Image Synthesis and Analysis (LISA) and the Erasme Hospital
Contact: Olivier Debeir < odebeir@ulb.ac.be> & Olivier Van Hove < Olivier.Van.Hove@erasme.ulb.ac.be>

Orianne BASTIN - Olivier DEBEIR - Rudy ERCEK- Ken HASSELMANN - Jean LANDERCY - Antoine NONCLERCQ - Michel OSEE - Francois QUITIN

ULB
" We are developing a prototype, upon the request of Médecins Sans Frontières | MSF Belgique, with aim to monitor key parameters of a patient's health - levels of oxygen saturation in the blood, heart rate and temperature - in order to detect a potential covid19 infection, and to adapt the patient care accordingly. The prototype is wearable, battery powered, and send its data wirelessly. In this regard, the patient can be remotely monitored. "
Funding: Own funds
Publication References: None.
Contact: Primary contact: Antoine Nonclercq - anoncler@ulb.ac.be ULB BEAMS (Oriane Bastin - orianne.bastin@ulb.ac.be & Ken Hasselmann - ken.hasselmann@ulb.ac.be & Antoine Nonclercq - anoncler@ulb.ac.be & Michel Osée - mosee@ulb.ac.be & François Quitin - fquitin@ulb.ac.be) ULB LISA (Olivier Debeir - odebeir@ulb.ac.be & Rudy Ercek - rercek@ulb.ac.be) ULB Smart Campus (Jean Landercy - Jean.Landercy@ulb.be)

Vincent Raussens, FNRS Senior Research Associate - Ivan Jabin, Doctor - Gilles Bruylants, Doctor - Pascale Blond

ULB - FNRS
" Germanium is widely used for attenuated total reflection (ATR) Fourier infrared transform spectroscopy (FTIR). We developed a simple way using calixarenes to functionalize these Ge surfaces and transform them in high quality and sensitive biosensors. The detection being done by ATR-FTIR allows the high sensitivity but also can quantify different molecular species in a mixture as well as their different secondary structures, both being extremely important for epidemiology study (it has been demonstrated that FTIR can discriminate different Ig proteins in a mixture). The recording of the spectra takes only few seconds and their analysis can be easily automatized. Furthermore, our laboratory is equipped for rapid and high-throughput analysis (fabrication of protein micro-arrays, infrared microscope able to record hundreds of spectra simultaneously, …). This new generation of biosensor has also the great advantage of being extremely stable and recyclable . All these...

Vincent Raussens, FNRS Senior Research Associate - Pascale Blond - Olivier Denis, Doctor

ULB and Sciensano - FNRS
" La spectroscopie IR fournit des signatures spectroscopiques spécifiques permettant une détection rapide de biomolécules dans un échantillon complexe, tout en ne requérant que très peu de matériel. La création d'un biosenseur basé sur cette méthode et appliqué aux anticorps contre le SARS-COV-2, permettrait d'étudier de manière beaucoup plus sensible, spécifique et quantitative les réponses immunologiques de la population contre le SARS-COV-2 que les tests sérologiques actuels. C'est un enjeu majeur pour gérer la période de déconfinement. "
Funding: Demande en attente auprès de l'AUF
Contact: Vincent Raussens Senior Research Associate (FRS-FNRS Belgium) Université libre de Bruxelles Structure and Function of Biological Membranes bd. du Triomphe, Access 2 - 1050 Brussels, Belgium T : +32 (0)2 650 53 86 vrauss@ulb.ac.be

Contact us

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info@COVID19-WB.be

Brussels & Wallonia against COVID19

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