UMONS/ Epicura/ CHU Ambroise Paré/ Hôpital Foch
" In recent weeks, many European ear, nose and throat (ENT) specialists and infectious diseases specialists have observed that patients infected with coronavirus (COVID-19) had impaired sense of smell and taste. These symptoms of anosmia and dysgeusia were found in a large number of patients infected in Germany, France, Italy, Spain, England and the USA. Faced with the multiplication of declarations medical press, a group of ENT specialists from IFOS (the International Federation of ORL Societies), has developed a survey to investigate these sense of smell and taste disorders in patients infected with COVID-19 (infection being proven by PCR test). Pr. Sven Saussez and Dr. Jérôme Lechien from the University of Mons coordinated this study which was conducted by 33 ENT physicians and researchers in 12 European hospital "
Funding: CUR project submitted UMONS funding
Publication References: Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A, Dequanter D, Blecic S, El Afia F, Distinguin L, Chekkoury-Idrissi Y, Hans S, Delgado IL, Calvo-Henriquez C, Lavigne P, Falanga C, Barillari MR, Cammaroto G, Khalife M, Leich P, Souchay C, Rossi C, Journe F, Hsieh J, Edjlali M, Carlier R, Ris L, Lovato A, De Filippis C, Coppee F, Fakhry N, Ayad T, Saussez S. Eur Arch Otorhinolaryngol. 2020 Apr 6:1-11. doi: 10.1007/s00405-020-05965-1. Online ahead of print. PMID: 32253535 Free PMC article. Acute urticaria with pyrexia as the first manifestations of a COVID-19 infection. van Damme C, Berlingin E, Saussez S, Accaputo O. J Eur Acad Dermatol Venereol. 2020 Apr 24. doi: 10.1111/jdv.16523. Online ahead of print. Sniffing out the evidence; It's now time for public health bodies recognize the link between COVID-19 and smell and taste disturbance. Lechien JR, Hopkins C, Saussez S. Rhinology. 2020 Apr 30. doi: 10.4193/Rhin20.159. Online ahead of print. Clinical and Epidemiological Characteristics of 1,420 European Patients with mild-to-moderate Coronavirus Disease 2019. Lechien JR, Chiesa-Estomba CM, Place S, Van Laethem Y, Cabaraux P, Mat Q, Huet K, Plzak J, Horoi M, Hans S, Barillari MR, Cammaroto G, Fakhry N, Martiny D, Ayad T, Jouffe L, Hopkins C, Saussez S; COVID-19 Task Force of YO-IFOS. J Intern Med. 2020 Apr 30. doi: 10.1111/joim.13089. Online ahead of print. "Anosmia is a key symptom of COVID-19 infection and should be used as a diagnostic tool" Jerome R. Lechien, MD, PhD, MSc1, 2, Maria Rosaria Barillari MD, PhD, MS3, Lionel Jouffe1,4, Sven Saussez, MD, PhD2,5 Accepté dans Ear Nose Throat Journal. Psychophysical Olfactory Tests and Detection of COVID-19 in Patients with Sudden Onset Olfactory Dysfunction: A Prospective Study. Jerome R. Lechien MD, PhD, MS1-4*, Pierre Cabaraux MD1-5*, Carlos M. Chiesa-Estomba MD, MS1,6, Mohamad Khalife MD1,7, Jan Plzak MD, PhD8, Stéphane Hans MD, PhD, MS1,3, Delphine Martiny FarmD, PhD9, Christian Calvo-Henriquez MD1,10, Maria R. Barillari MD, PhD, MS1,11, Claire Hopkins MD, PhD12,13, Sven Saussez, MD, PhD1,2,4. Accepté dans Ear Nose Throat Journal. Objective Olfactory Evaluation of Self-reported Loss of Smell in a Case Series of 86 COVID-19 Patients Jerome R. Lechien, MD, PhD, MS1-4, Pierre Cabaraux MD1-5, Carlos M. Chiesa-Estomba MD, MS1,6, Mohamad Khalife MD1,7, Stéphane Hans, MD, PhD, MS1,3, Christian Calvo-Henriquez, MD1,8, Delphine Martiny, PharmD, PhD9, Fabrice Journe, PhD1,2, Leigh Sowerby, MD, MHM, FRCSC1,10, Sven Saussez, MD, PhD2,4,7 Accepté dans Head and Neck. Letter to the Editor about the Beltrán-Corbellini et al. publication :"Acute-onset smell and taste disorders in the context of Covid-19: a pilot multicenter PCR-based case-control study" (Eur J Neurol. 2020. doi: 10.1111/ene.14273.). Jerome R. Lechien, MD, PhD, MSc1-4, Claire Hopkins FRCS(ORLHNS) DM(Oxon)5, Sven Saussez, MD, PhD1,2,4 Accepté dans l'European J Neurol.
Contact: Pr. Sven Saussez, Head of the laboratory of human anatomy and experimental oncology. sven.saussez@umons.ac.be